University of Michigan-Ann Arbor · NeuroscienceALS Immunoexposome Lab
Stephen Goutman · Ann Arbor, Michigan
Research Focus
Dr. Stephen Goutman's lab at the University of Michigan focuses on understanding amyotrophic lateral sclerosis (ALS), a debilitating neurological condition, by investigating the role of the immune system and environmental exposures. The lab aims to develop diagnostic tools and therapeutic strategies based on immune signatures and occupational risks associated with ALS, utilizing advanced technologies like spectral flow cytometry to analyze immune profiles in patients. Their research seeks to enhance predictions of disease progression and inform prevention strategies for individuals at higher risk of developing ALS.
ALSimmune profilingspectral flow cytometryoccupational healthexposomebiomarkersdisease progressiontherapeutics
Research Aims
5AIM 01Characterize immune profiles in ALS patients using spectral flow cytometry.
AIM 02Establish a longitudinal cohort of individuals at higher risk for ALS.
AIM 03Investigate the interactions between occupational exposures and genetic risks related to ALS.
AIM 04Identify new biomarkers for ALS progression and personalized therapeutics.
AIM 05Assess the contributions of lifestyle factors to ALS risk and prevention.
Skills the Lab Values
spectral flow cytometryimmunophenotypinglongitudinal cohort studiesexposure assessmentgenotypingbioinformaticsdata analysisclinical outcome modeling
Output against the department
Publications126bottom 45% of dept.369th of 671
this lab
most publishedleast published
Citations6.9kbottom 47% of dept.354th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.