University of Florida · Biomedical EngineeringEnzyme Therapeutics and Immunology Unit
Benjamin George Keselowsky · Gainesville, Florida
Research Focus
Dr. Benjamin Keselowsky's lab focuses on developing advanced enzyme therapies to treat psoriasis, a chronic inflammatory skin condition. The lab studies both tissue-anchored and circulating forms of these enzymes to understand how they can effectively reduce inflammation and restore metabolic balance in immune cells. By innovatively engineering these therapeutic proteins, the lab seeks to bring new solutions to patients suffering from autoimmune diseases.
enzyme therapypsoriasisimmunotherapymetabolic programmingautoimmune diseases
Research Aims
5AIM 01Develop innovative fusion protein enzyme constructs for therapy.
AIM 02Investigate the effects of tissue-anchored versus circulating enzyme forms.
AIM 03Quantify cellular mechanisms of action in inflammation resolution.
AIM 04Evaluate therapeutic efficacy in reducing chronic inflammation.
AIM 05Explore new treatment options for autoimmune diseases like psoriasis.
Skills the Lab Values
protein engineeringcell cultureimmunofluorescenceenzyme assaysdata analysismetabolic profiling
Output against the department
Publications109bottom 20% of dept.477th of 595
this lab
most publishedleast published
Citations6.3kbottom 48% of dept.310th of 595
this lab
most citedleast cited
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