Georgia Institute of Technology-Main Campus · Engineering · ChemistrySingh Lab
Ankur Singh · Atlanta, Georgia
Research Focus
Dr. Ankur Singh's lab at Georgia Tech focuses on improving our understanding of immune responses, particularly in B cells, which are crucial for fighting infections and diseases like lymphoma. They develop innovative hydrogel-based structures that mimic lymphoid tissues to study how human B cells can be activated and sustained over time. This research aims to address significant challenges in vaccine development and racial disparities in cancer outcomes.
B cell activationimmune organoidslymphomavaccine developmenthydrogel technologycancer disparitiesimmunologyaged immune responseepigeneticsgerminal center differentiation
Research Aims
5AIM 01Develop hydrogel-based lymphoid tissue models to generate activated human B cells.
AIM 02Investigate the genetic and environmental factors affecting lymphoma outcomes, particularly in African-American populations.
AIM 03Create organoids that mimic the lymph node microenvironment to understand immune interactions in aging.
AIM 04Study the mechanisms of B cell receptor signaling in relation to cancer treatment resistance.
AIM 05Evaluate the effectiveness of engineered B cells in therapeutic applications.
Skills the Lab Values
cell culturehydrogel fabricationimmune organoid generationB cell assaysin vivo animal modelsmolecular biology techniquesflow cytometryPCRgenomicsdata analysis
Output against the department
Publications125bottom 28% of dept.351st of 493
this lab
most publishedleast published
Citations4.8kbottom 37% of dept.313th of 493
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.