University of California-Davis · BiochemistryTumor Microenvironment Therapeutics Lab
Kit S Lam · Davis, California
Research Focus
The lab led by Dr. Kit S. Lam focuses on developing innovative therapeutic strategies to enhance cancer treatment, specifically by targeting the tumor microenvironment using transformable nanoparticles. By utilizing a unique platform that adjusts its structure in response to specific tumor markers, the lab aims to deliver treatments that activate the immune system against cancer while minimizing damage to normal tissues. Their research is particularly relevant to the treatment of non-small cell lung cancer.
tumor microenvironmentnanoparticlescancer immunotherapypeptide ligandsbioorthogonal chemistry
Research Aims
3AIM 01Design and synthesize nanostructures that target specific cancer receptors.
AIM 02Optimize the delivery platform for enhanced cancer immunotherapy using imaging techniques.
AIM 03Assess the effectiveness and safety of the therapeutic approach in mouse cancer models.
Skills the Lab Values
nanoparticle synthesisimmunohistochemistryin vivo imagingbiochemical assaystumor modelsdrug delivery systemsoptical imagingmolecular characterizationprotein engineeringimmunological techniques
Output against the department
Publications672top 5% of dept.20th of 402
this lab
most publishedleast published
Citations24ktop 16% of dept.63rd of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.