University of California-San Francisco · BiologyOhmann Morphogenesis Lab
Jeffrey Ohmann Bush · San Francisco, California
Research Focus
Dr. Jeffrey Ohmann Bush's research lab at UCSF focuses on understanding how the cells shape the craniofacial structure during development and what goes wrong in craniofacial congenital anomalies. Using innovative techniques, including live imaging and CRISPR, the lab investigates the cellular behaviors and signaling mechanisms that lead to these birth defects. The goal is to translate this knowledge into improved therapeutic strategies for treating craniofacial conditions.
craniofacial morphogenesiscongenital anomaliesCRISPR/Cas9cellular behaviorhuman stem cells
Research Aims
3AIM 01Understand the control of mesenchymal cell movement in craniofacial tissue shaping
AIM 02Elucidate mechanisms of epithelial tissue fusion in craniofacial development
AIM 03Identify novel regulators of craniofacial morphogenesis using CRISPR technology
Skills the Lab Values
live cell imagingCRISPR gene editingcell culturehuman induced pluripotent stem cells (hiPSCs)tissue engineering
Output against the department
Publications82bottom 25% of dept.776th of 1,033
this lab
most publishedleast published
Citations2.5kbottom 18% of dept.844th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.