Dartmouth College · Microbiology & ImmunologyFungal Pathogenicity Research Lab
Robert Andrew Cramer · Hanover, New Hampshire
Research Focus
Dr. Robert Cramer's lab at Dartmouth College focuses on understanding and overcoming fungal infections, particularly those caused by the mold Aspergillus fumigatus, which can be deadly for immunocompromised patients. The lab develops new antifungal drugs that are effective against drug-resistant strains of moulds and studies how certain cancer therapies can influence fungal pathogenicity. They combine chemical biology, genetic analysis, and mouse models to tackle these pressing health issues.
fungal infectionsantifungal drugsAspergillus fumigatusdrug resistanceimmune-targeted therapies
Research Aims
4AIM 01Develop new antifungal compounds to combat drug-resistant mould infections.
AIM 02Investigate the genetic factors that determine pathogenicity of Aspergillus fumigatus during immune suppression.
AIM 03Optimize small molecule antifungals to enhance their efficacy against pathogenic moulds.
AIM 04Characterize the interaction between Aspergillus fumigatus and host immune cells in the context of cancer therapies.
Skills the Lab Values
chemical synthesishigh-throughput screeningin vitro assaysgenetic engineeringmurine modelsbioinformaticsdrug testingimmunoassays
Output against the department
Publications2bottom 2% of dept.478th of 486
this lab
most publishedleast published
Citations0bottom 1% of dept.484th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.