Harvard University · BiologyOlfactory Neural Dynamics Lab
Sandeep R Datta · Cambridge, Massachusetts
Research Focus
Dr. Sandeep R Datta's lab at Harvard Medical School focuses on understanding how the brain processes and interprets olfactory (smell) information, as well as studying behavioral changes in Alzheimer's disease. The lab uses innovative techniques like single cell sequencing and advanced motion analysis to explore how sensory systems adapt and how behavioral patterns are affected by neurological conditions. Students in the lab will learn about the intersection of molecular biology, neuroscience, and behavior.
olfactory systemAlzheimer's diseasegene expressionmachine learningbehavioral phenotyping
Research Aims
3AIM 01Characterize how olfactory sensory neurons adapt their gene expression in response to different environments.
AIM 02Investigate the signaling mechanisms linking olfactory neuron activity to long-term changes in gene expression.
AIM 03Utilize advanced motion analysis to identify behavioral changes in Alzheimer's disease mouse models.
Skills the Lab Values
single cell sequencingfunctional imagingmachine learningmouse modelstranscriptomics
Output against the department
Publications140top 49% of dept.507th of 1,033
this lab
most publishedleast published
Citations25ktop 15% of dept.156th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.