Johns Hopkins University · Microbiology & ImmunologyCoppens Lipid Lab
Isabelle Coppens · Baltimore, Maryland
Research Focus
Dr. Isabelle Coppens leads a research lab at Johns Hopkins University that focuses on understanding how the Toxoplasma gondii parasite survives inside host cells. Her team investigates the ways in which this parasite hijacks lipid transport mechanisms from mammalian cells, allowing it to acquire essential nutrients for survival. This research has implications for developing treatments against Toxoplasma and enhancing our understanding of cellular processes.
Toxoplasma gondiilipid traffickinghost-parasite interactionintracellular survivalmembrane contact sites
Research Aims
3AIM 01Outline the molecular machineries Toxoplasma uses to intercept host vesicular pathways.
AIM 02Investigate the formation and function of membranous tubules linked to the parasitophorous vacuole.
AIM 03Examine non-vesicular lipid transfer mechanisms involving membrane contact sites.
Skills the Lab Values
cell cultureimmunofluorescence microscopymolecular biology techniqueslipid extractiongenetic manipulation
Output against the department
Publications239top 25% of dept.121st of 486
this lab
most publishedleast published
Citations24ktop 15% of dept.73rd of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.