University of Michigan-Ann Arbor · ChemistryBrooks Biophysics Lab
Charles L Brooks · Ann Arbor, Michigan
Research Focus
Dr. Charles L. Brooks' lab focuses on using computer simulations to study biological molecules and how they interact, particularly in the context of drug design and cellular processes. By developing advanced theoretical methods, the team aims to better understand how small molecules can affect proteins and other biological systems, which is crucial for biomedical research and drug discovery. Collaborations with experimental labs allow for practical applications and validations of their computational approaches.
computer simulationsbiomoleculesdrug designligand bindingprotein interactionsthermodynamicsmolecular dynamicsbiomedical research
Research Aims
5AIM 01Explore receptor-ligand interactions to enhance drug design.
AIM 02Develop methods for pH-dependent modeling of biological processes.
AIM 03Improve software for molecular simulations to assist the biomedical community.
AIM 04Collaborate on experimental validations of computational findings.
AIM 05Refine methods for analyzing protein dynamics and interactions.
Skills the Lab Values
computer simulationmolecular dynamicsfree energy calculationscomputational modelingsoftware developmentligand-receptor dockingdata analysis in big dataalgorithm developmentthermodynamic modeling
Output against the department
Publications673top 9% of dept.20th of 216
this lab
most publishedleast published
Citations60ktop 5% of dept.10th of 216
this lab
most citedleast cited
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