Case Western Reserve University · Biomedical EngineeringMoffitt Lab
Michael Moffitt · Cleveland, Ohio
Research Focus
Dr. Michael Moffitt's lab at Case Western Reserve University focuses on using light to treat chronic pain through a technique called photobiomodulation (PBM). The lab investigates how specific wavelengths of light can temporarily block pain signals in nerves, exploring the underlying biological mechanisms and working towards developing implantable devices for clinical use. Their research aims to enhance understanding of nerve function and pain relief, ultimately contributing to better pain management therapies.
photobiomodulationneuropathic painchronic painaxonal blockpain signaling
Research Aims
5AIM 01Characterize the effects of PBM on axonal function in nerve preparations.
AIM 02Explore the role of microtubule destabilization in pain signal modulation.
AIM 03Develop pre-clinical systems for chronic PBM applications in pain treatment.
AIM 04Evaluate the effectiveness of PBM in an animal model of chronic pain.
AIM 05Investigate the relationship between PBM dosing and pain relief outcomes.
Skills the Lab Values
confocal microscopyelectron microscopyrodent pain modelscomputational modelingimplantable device development
Output against the department
Publications41bottom 5% of dept.568th of 595
this lab
most publishedleast published
Citations845bottom 5% of dept.566th of 595
this lab
most citedleast cited
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