UCUniversity of Cincinnati-Main Campus · Biology
The Pulmonary Imaging Lab
Nalinikanth Kotagiri · Cincinnati, Ohio
Research Focus
Dr. Nalinikanth Kotagiri's lab focuses on innovative imaging techniques to improve the diagnosis and treatment of lung infections, particularly in patients with chronic obstructive pulmonary disease (COPD). The research involves developing specialized imaging probes that can identify specific bacteria causing infections, which are crucial for targeted therapies. By using cutting-edge imaging technologies, the lab aims to differentiate between bacterial and viral infections, thereby enhancing treatment outcomes and patient management.
pulmonary infectionsCOPDimaging probesKlebsiella pneumoniaePseudomonas aeruginosametallophoresPET imagingbacterial infectionsco-infection modelsantibiotic responsiveness
Research Aims
5AIM 01Develop pathogen-specific PET imaging probes for detecting bacterial infections in COPD patients.
AIM 02Differentiate between bacterial and viral infections non-invasively using imaging techniques.
AIM 03Evaluate the responsiveness of imaging probes to various antibiotics in preclinical models.
AIM 04Investigate the colonization of bacteria in patients with AECOPD using targeted imaging methods.
AIM 05Lay the foundation for new technologies utilizing metallophores as contrast agents in medical imaging.
Skills the Lab Values
molecular imagingcell culturemouse modelsinfection modelingantibiotic sensitivity testingPET imaging techniquesbacterial culturedata analysis for imagingsputum analysismetallophore characterization
Output against the department
Publications42bottom 9% of dept.941st of 1,033
this lab
most publishedleast published
Citations1.2kbottom 6% of dept.968th of 1,033
this lab
most citedleast cited
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