University of Kansas · Microbiology & ImmunologyQiu Lab
Jianming Qiu · Lawrence, Kansas
Research Focus
Dr. Jianming Qiu's lab specializes in developing innovative gene editing therapies for cystic fibrosis (CF), a genetic disorder affecting the lungs. The lab focuses on using advanced techniques like CRISPR and rAAV vectors to correct genetic mutations in patients. Their research aims to enhance gene therapy effectiveness, making it a feasible treatment option for all CF patients, regardless of their specific gene mutations.
cystic fibrosisgene editingCRISPRrAAV therapygene therapyairway progenitor cellsHITImutant vector developmenttransduction enhancement
Research Aims
5AIM 01Develop gene editing therapies to correct CFTR mutations in cystic fibrosis patients.
AIM 02Enhance the efficiency of rAAV vectors for gene therapy applications.
AIM 03Investigate the application of HITI to overcome current gene editing limitations.
AIM 04Create next-generation rAAV variants for improved transduction of airway cells.
AIM 05Assess the therapeutic potential using in vitro and in vivo cystic fibrosis models.
Skills the Lab Values
CRISPRgene editingcell culturerAAV vector designhomology-independent targeted integration (HITI)mutant library screeninganimal models (ferret)molecular cloninggenetic engineering
Output against the department
Publications221top 28% of dept.137th of 486
this lab
most publishedleast published
Citations9.1ktop 40% of dept.192nd of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.