University of California-Irvine · Biomedical EngineeringThe HeartFlow Lab
Arash Kheradvar · Irvine, California
Research Focus
Dr. Arash Kheradvar's lab focuses on innovative heart valve tissue engineering and understanding the mechanics of heart function in diseases like pulmonary arterial hypertension. His research aims to develop living tissue valves that can better mimic native heart valves and to non-invasively monitor right ventricle function in patients with heart disease. They aim to improve patient outcomes by enhancing the performance and longevity of heart valves and utilizing advanced imaging techniques for clinical monitoring.
tissue engineeringheart valvespulmonary arterial hypertension3D echocardiographyventricular functionhemodynamicsbiomechanicsvalvular heart diseasevortex flow
Research Aims
5AIM 01Develop tissue-engineered heart valves that improve cell viability and tissue generation.
AIM 02Characterize the effects of vortex flow on the performance of heart valves.
AIM 03Utilize non-invasive imaging to monitor right ventricle function in pulmonary arterial hypertension patients.
AIM 04Assess the accuracy of novel 3D imaging techniques compared to traditional methods.
AIM 05Investigate the relationship between RV energy state and patient clinical status in PAH.
Skills the Lab Values
tissue engineering techniques3D echocardiographyhemodynamic assessmentcell culturescaffold fabricationcomputational fluid dynamicsanimal modelingdata analysisimage processing
Output against the department
Publications147bottom 32% of dept.405th of 595
this lab
most publishedleast published
Citations4.2kbottom 32% of dept.402nd of 595
this lab
most citedleast cited
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