Stanford University · Biomedical EngineeringLe Lab
Quynh-Thu Xuan Le · Stanford, California
Research Focus
Dr. Quynh-Thu Xuan Le's research lab at Stanford University focuses on improving radiotherapy for cancer treatment. By studying how cancer and normal tissues respond to radiation, the lab aims to protect healthy cells while enhancing the effectiveness of therapies against tumors. They are investigating various molecular strategies, including the use of natural compounds and genetic pathways, to develop more effective cancer treatments with fewer side effects.
radiotherapytumor genomicsnormal tissue protectioncancer treatmenthead and neck cancerlung cancerglutaminaseALDH3A1FTO inhibition
Research Aims
4AIM 01Investigate the role of C5aR1 inhibition in enhancing radiosensitivity of tumors while protecting normal tissues.
AIM 02Test d-limonene's effectiveness in reducing radiotherapy-induced dry mouth in head and neck cancer patients.
AIM 03Develop a personalized radiosensitization strategy for non-small cell lung cancer based on genetic mutations.
AIM 04Examine the effects of FTO inhibition on cancer cell growth and radiation sensitivity in various tumor models.
Skills the Lab Values
cell cultureclinical trial designmolecular biology techniquesRNA sequencingcancer modelinganimal modelsdata analysis with machine learningflow cytometrydrug formulation
Output against the department
Publications1,019top 5% of dept.27th of 595
this lab
most publishedleast published
Citations43ktop 5% of dept.28th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.