Washington University in St Louis · Biomedical EngineeringAdvanced Imaging and Mitochondrial Function Lab
Vijay Sharma · Saint Louis, Missouri
Research Focus
Dr. Vijay Sharma's lab focuses on developing advanced PET imaging techniques to investigate the role of oxidative stress and inflammation in various diseases, particularly neurodegenerative disorders like Alzheimer's and chemotherapy-induced cardiotoxicity. The research aims to create novel imaging agents that can help visualize cellular processes related to mitochondrial function and response to treatments. By utilizing these new imaging tools, the lab hopes to enhance early diagnosis and improve the management of chronic diseases.
PET imagingneurodegenerative diseasesoxidative stressmitochondrial functionchemotherapy cardiotoxicity
Research Aims
5AIM 01Develop PET tracers for imaging brain inflammation
AIM 02Investigate chemotherapy-induced cardiotoxicity
AIM 03Evaluate pharmacokinetics of new PET tracers
AIM 04Assess imaging characteristics in human subjects
AIM 05Produce clinical doses of PET radiopharmaceuticals
Skills the Lab Values
PET imaging techniquesmolecular imagingcell cultureanimal modelsfluorescence imagingdata analysispharmacokineticsdosimetry studiesGMP productionhuman imaging studies
Output against the department
Publications1,019top 5% of dept.26th of 595
this lab
most publishedleast published
Citations28ktop 10% of dept.61st of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.