New York University · Microbiology & ImmunologyAntiviral Mechanisms Research Group
Benjamin R. Tenoever · New York, New York
Research Focus
Dr. Benjamin R. Tenoever's lab focuses on how cells defend themselves against viral infections. They study a complex formed by the enzyme Drosha and the RNA-induced silencing complex, known as the ADAR-RISC Complex, which plays a role in antiviral responses. By understanding how this complex works, researchers hope to develop new therapies that can better combat viral diseases.
antiviral responseADAR1DroshaRISC complexRNA interference
Research Aims
5AIM 01Characterize the ADAR-RISC Complex in viral infection responses.
AIM 02Investigate the physiological relevance of the Drosha-containing structure.
AIM 03Understand the role of RNA molecules in antiviral defense mechanisms.
AIM 04Analyze interactions between host and viral proteins.
AIM 05Explore potential therapeutic applications of the findings.
Skills the Lab Values
cell cultureRNA extractionbiochemical assaysimmunoprecipitationfluorescence microscopy
Output against the department
Publications192top 33% of dept.162nd of 486
this lab
most publishedleast published
Citations22ktop 17% of dept.83rd of 486
this lab
most citedleast cited
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