University of Connecticut · Biomedical EngineeringElastin Mechanics Lab
Anna Tarakanova · Storrs, Connecticut
Research Focus
Dr. Anna Tarakanova's research focuses on understanding the structure and mechanics of elastin, a protein that allows arteries to stretch and recoil, providing efficient blood circulation. By investigating how aging and disease impact elastin's properties, her lab aims to develop new strategies for preventing and treating cardiovascular issues. The research combines advanced modeling techniques and experimental approaches to uncover the connections between molecular structure and function in arterial tissues.
elastinarterial mechanicsagingbiomedical engineeringvascular healthmolecular modelingbiomechanical testingdisease mechanismscrosslinking
Research Aims
3AIM 01Identify aging-associated damage sites in elastin and understand their mechanical effects.
AIM 02Determine the role of enzymatic and non-enzymatic crosslinks on elastin mechanics.
AIM 03Investigate how microscale fiber mechanics impact the architecture of elastic tissues during aging.
Skills the Lab Values
molecular modelingbiochemical characterizationmultiscale biomechanical testingoptical imagingdata analysismathematical modelingexperimental designprotein characterizationtissue mechanics
Output against the department
Publications71bottom 9% of dept.539th of 595
this lab
most publishedleast published
Citations2.0kbottom 14% of dept.510th of 595
this lab
most citedleast cited
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