University of Maryland, Baltimore · Microbiology & ImmunologyLi Vaccine Lab
Yuxing Li · Baltimore, Maryland
Research Focus
Dr. Yuxing Li's lab focuses on designing safer and more effective vaccines for the Zika virus, a significant public health threat. The research primarily investigates how antibodies interact with the virus and aims to develop a vaccine that not only provides strong immunity but also avoids potential issues seen with dengue virus infections. The lab employs advanced techniques to analyze immune responses and antibody dynamics in order to enhance vaccine efficacy.
Zika virusvaccine designflavivirusantibody responseneutralizing antibodiesimmune responseantibody-dependent enhancementimmunogenicity
Research Aims
5AIM 01Analyze B cell responses to Zika virus to improve vaccine design.
AIM 02Develop novel vaccine candidates with reduced risk of antibody-dependent enhancement.
AIM 03Investigate the structural interactions between Zika virus proteins and antibodies.
AIM 04Evaluate the efficacy of vaccine candidates in small animal models.
AIM 05Enhance understanding of immune responses to flavivirus infections.
Skills the Lab Values
immunology techniquescell culturemouse modelsflow cytometrymolecular cloningprotein engineeringX-ray crystallographyin vitro assayscryoelectron microscopy
Output against the department
Publications89bottom 30% of dept.342nd of 486
this lab
most publishedleast published
Citations7.0ktop 50% of dept.245th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.