University of Pennsylvania · PharmacologyTRPV Channel Research Laboratory
Vera Moiseenkova-Bell · Philadelphia, Pennsylvania
Research Focus
Vera Moiseenkova-Bell's lab at the University of Pennsylvania focuses on understanding the TRPV channels, particularly TRPV2 and TRPV5, which are important for various physiological processes. The research aims to uncover the molecular mechanisms that control these channels' functions, particularly in neurons and immune cells. By using advanced techniques in biochemistry and imaging, the lab seeks to determine how these channels operate at the atomic level, which could have significant implications for health and disease.
TRPV channelscalcium signalingneuron developmentimmunitykidney physiologymembrane proteinbiophysicscellular functionelectrophysiologymass spectrometry
Research Aims
5AIM 01Investigate how TRPV2 and TRPV5 channels are gated by various modulators.
AIM 02Explore the physiological roles of TRPV channels in neurons and immune cells.
AIM 03Elucidate the differences in function and localization between TRPV2 and TRPV5.
AIM 04Characterize the structural details of TRPV channels using cutting-edge imaging techniques.
AIM 05Understand the implications of TRPV channels in health and disease.
Skills the Lab Values
membrane protein biochemistrycryo-electron microscopyflow cytometryconfocal fluorescence microscopyelectrophysiological methodsmass spectrometryproximity labelingcell cultureanalytical techniquesmicroscopy
Output against the department
Publications114bottom 31% of dept.317th of 462
this lab
most publishedleast published
Citations3.1kbottom 24% of dept.353rd of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.