University of Delaware · EngineeringInnovative Drug Delivery Unit
Kristi L Kiick · Newark, Delaware
Research Focus
Dr. Kristi Kiick's lab at the University of Delaware focuses on developing innovative drug delivery systems to treat post-traumatic osteoarthritis (PTOA). Their research aims to create a new way to deliver medications directly to injured joints in a controlled manner, which could significantly improve outcomes for patients suffering from joint injuries. By using collagen-targeting techniques and temperature-responsive materials, the lab hopes to enhance the effectiveness of existing drugs and reduce their rapid clearance from the body.
osteoarthritisdrug deliverycollagenthermoresponsivebiocompatibilitynanovesiclesintra-articular injectionchondrocytespharmaceutical intervention
Research Aims
5AIM 01Develop drug delivery systems that target injured joints.
AIM 02Evaluate the stability of drug-loaded nanovesicles.
AIM 03Assess the effectiveness of drugs in reducing PTOA markers.
AIM 04Investigate the pharmacokinetics of drug release in joint tissues.
AIM 05Characterize the biocompatibility of new drug delivery methods.
Skills the Lab Values
cell culturenanoparticle formulationmicroscopyin vivo modelingdrug release assayshistologyimmunohistochemistrybiocompatibility testingthermoresponsive materials
Output against the department
Publications239top 37% of dept.102nd of 278
this lab
most publishedleast published
Citations12ktop 31% of dept.87th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.