University of Illinois Chicago · ChemistryLipid Signaling and Protein Interaction Lab
Wonhwa Cho · Chicago, Illinois
Research Focus
Dr. Wonhwa Cho's lab at the University of Illinois at Chicago focuses on how lipids regulate the interactions between proteins in cells. Their research investigates the role of membrane lipids, like cholesterol, in controlling cellular signaling pathways, which are essential for normal health and can lead to diseases like cancer when disrupted. By understanding these lipid-protein interactions better, the lab aims to develop innovative strategies for drug discovery that could significantly impact treatment options for various human diseases.
lipid signalingprotein interactionscell signalingdrug discoverycancer biologymembrane lipidsprotein complexescholesterolphosphoinositides
Research Aims
4AIM 01Investigate how lipids regulate protein-protein interactions in cells.
AIM 02Elucidate the mechanisms of lipid-mediated cellular signaling.
AIM 03Develop innovative strategies for drug targeting based on lipid-protein interactions.
AIM 04Explore the physiological significance of protein interaction domains in health and disease.
Skills the Lab Values
protein-protein interaction assayslipid imaging technologycell culturemolecular cloningWestern blotimmunoprecipitationfluorescence microscopybiochemical assaysdata analysis in R or Python
Output against the department
Publications118bottom 25% of dept.161st of 216
this lab
most publishedleast published
Citations6.6kbottom 41% of dept.127th of 216
this lab
most citedleast cited
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