Rutgers University-New Brunswick · Biomedical EngineeringFeng Cancer Lab
Zhaohui Feng · New Brunswick, New Jersey
Research Focus
Dr. Zhaohui Feng's lab at Rutgers focuses on understanding colorectal cancer, particularly the role of a protein called Parkin in cancer progression. Parkin is often downregulated in colorectal cancer, and the lab aims to explore how this affects cancer development and how it can be targeted for therapy. Their research combines advanced screening methods and mouse models to uncover new treatment strategies for colorectal cancer, especially in cases where Parkin is deficient.
colorectal cancerParkinmetabolic reprogrammingubiquitinationtherapeutic strategiessmall molecule inhibitors
Research Aims
5AIM 01Investigate the mechanisms by which Parkin suppresses colorectal cancer.
AIM 02Identify novel metabolic pathways affected by Parkin in cancer cells.
AIM 03Develop therapeutic strategies for treating Parkin-deficient colorectal cancer.
AIM 04Test the efficacy of small molecule inhibitors in colorectal cancer models.
AIM 05Evaluate the role of Parkin in the progression of colorectal cancer.
Skills the Lab Values
cell culturemouse modelsLC-MS/MSquantitative proteomicsCRISPRorganoid culturebiological assaysprotein-protein interaction analysissmall molecule screening
Output against the department
Publications159bottom 35% of dept.384th of 595
this lab
most publishedleast published
Citations19ktop 19% of dept.112th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.