Ohio State University-Main Campus · Microbiology & ImmunologyMucosal Vaccine Innovations Lab
Purnima Dubey · Columbus, Ohio
Research Focus
Dr. Purnima Dubey's research lab at Ohio State University focuses on developing advanced vaccines to combat respiratory infections, particularly those caused by SARS-CoV-2 and Bordetella pertussis. The lab aims to create mucosal vaccines that not only provide immediate protection against these pathogens but also induce long-lasting immune responses. By exploring innovative adjuvants and novel immunogenic proteins, the research seeks to improve vaccine efficacy significantly and reduce transmission of these diseases.
SARS-CoV-2Bordetella pertussismucosal immunityvaccinesT cell responsesadjuvants
Research Aims
5AIM 01Develop mucosal subunit vaccines against SARS-CoV-2 that elicit strong immune responses.
AIM 02Identify novel immunogenic proteins from Bordetella pertussis for vaccine development.
AIM 03Test the efficacy of a novel pertussis vaccine in reducing nasal colonization in animal models.
AIM 04Evaluate the long-term immune responses generated by new vaccine candidates.
AIM 05Explore different adjuvants to improve vaccine-induced protection against respiratory pathogens.
Skills the Lab Values
PCRcell culturemouse modelsflow cytometryprotein purificationmass spectrometryimmunization techniquesantibody assaysbioinformaticsvaccine formulation
Output against the department
Publications105bottom 38% of dept.301st of 486
this lab
most publishedleast published
Citations2.1kbottom 13% of dept.422nd of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.