University of South Florida · PhysiologyLiu Kidney Lab
Ruisheng Liu · Tampa, Florida
Research Focus
Dr. Ruisheng Liu's lab focuses on kidney health, specifically how to protect and improve the function of transplanted kidneys and understand the transition from acute kidney injury (AKI) to chronic kidney disease (CKD). They use innovative techniques to assess and enhance kidney function, which is crucial since organ shortages are a major issue for patients needing transplants. Their research aims to develop new strategies to improve kidney survival and function during and after transplantation, while also investigating the regulatory mechanisms behind kidney response to injury.
kidney transplantationacute kidney injurychronic kidney diseaseNa/K ATPaseischemiamacula densatubuloglomerular feedbackcell repairelectric field modulation
Research Aims
5AIM 01Examine the protective effects of improved Synchronization Modulation Electric Field (i-SMEF) on transplanted kidney function.
AIM 02Investigate how i-SMEF enhances the recovery of injured kidney cells during ischemia.
AIM 03Test the role of NOS1 expression in the macula densa in the transition from AKI to CKD.
AIM 04Identify new therapeutic targets to prevent AKI to CKD transition.
AIM 05Elucidate the mechanisms regulating renal sodium excretion and blood pressure in response to kidney injury.
Skills the Lab Values
animal modelscell cultureelectrophysiologyimmunohistochemistrymolecular cloningWestern blottingRNA isolationdata analysissurgical techniques
Output against the department
Publications158top 46% of dept.132nd of 286
this lab
most publishedleast published
Citations2.7kbottom 19% of dept.232nd of 286
this lab
most citedleast cited
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