University of Iowa · BiologySonic Synapse Lab
Steven H Green · Iowa City, Iowa
Research Focus
Dr. Steven H Green's lab at the University of Iowa focuses on understanding how noise exposure affects hearing, particularly through the damage of cochlear synapses. They are investigating the role of sex hormones like progesterone in protecting against this type of damage and ways to promote synapse regeneration after noise trauma, with an emphasis on sex differences in susceptibility. This research could lead to new treatments for hearing impairments that result from noise exposure.
cochlear synapsesnoise-induced synaptopathyprogesteroneregenerationsex differences
Research Aims
3AIM 01Investigate the effects of progesterone levels on cochlear synaptopathy in male and female mice.
AIM 02Determine the optimal timing for administering treatments after noise exposure to promote synapse regeneration.
AIM 03Examine the molecular mechanisms by which progesterone and cyclic AMP signaling promote synapse regeneration.
Skills the Lab Values
cell culturemouse modelsin vitro experimentsWestern blotPCR
Output against the department
Publications53bottom 13% of dept.900th of 1,033
this lab
most publishedleast published
Citations3.5kbottom 27% of dept.756th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.