Vanderbilt University · EngineeringNanoImmuno Innovations
John Tanner Wilson · Nashville, Tennessee
Research Focus
Dr. John Tanner Wilson's lab at Vanderbilt University focuses on developing innovative nanoparticles to improve cancer immunotherapy and antiviral therapies. The lab is particularly interested in creating nanoparticles that activate the body's immune system through specific receptors, aiming to enhance treatment options for conditions like neuroblastoma and various viral illnesses. They work on optimizing these nanoparticles to ensure they effectively target and treat diseases while minimizing side effects.
nanoparticlesimmunotherapyneuroblastomacancer treatmentRIG-I pathwaydrug deliverySTING-activating nanoparticlesCRISPRpolymers
Research Aims
5AIM 01Develop nanoparticles that activate the RIG-I immune pathway to enhance therapeutic effects.
AIM 02Optimize the design of STING-activating nanoparticles for better treatment of neuroblastoma.
AIM 03Evaluate the efficacy of immunotherapy combinations in preclinical models.
AIM 04Enhance immune responses to cancer therapies through effective nanoparticle delivery.
AIM 05Address drug delivery challenges for immunotherapeutic agents.
Skills the Lab Values
nanoparticle engineeringpolymer chemistryanimal modelingimmune assay techniquesfluorescence microscopynanofabricationbiodistribution studiespharmacokineticsRNA delivery systems
Output against the department
Publications400top 17% of dept.47th of 278
this lab
most publishedleast published
Citations9.3ktop 39% of dept.109th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.