Johns Hopkins University · EngineeringRapid Diagnostic Innovations Lab
Tza-Huei Jeff Wang · Baltimore, Maryland
Research Focus
Dr. Tza-Huei Jeff Wang's lab focuses on developing cutting-edge diagnostic platforms to quickly identify bacterial infections and their antibiotic susceptibilities. By using advanced techniques like single-cell molecular analysis and microfluidics, the lab aims to provide faster and more accurate diagnoses for serious conditions like bacteremia and gonorrhea. This work is crucial for improving patient outcomes and tackling the growing problem of antibiotic resistance.
bacteremiaantibiotic resistancemicrofluidicssingle-cell analysisdiagnostic platformsantimicrobial susceptibility testingNeisseria gonorrhoeaemolecular diagnosticsrapid diagnosisRNA analysis
Research Aims
5AIM 01Develop a rapid bacterial detection device for diagnosing bacteremia.
AIM 02Create a platform for antimicrobial susceptibility testing that operates from clinical specimens.
AIM 03Use single-cell analysis to improve the speed of diagnosing gonorrhea.
AIM 04Integrate molecular diagnostics for timely and accurate antibiotic susceptibility results.
AIM 05Reduce the time needed for testing to enhance patient treatment outcomes.
Skills the Lab Values
PCRsingle-cell RT-PCRmicrofluidic chip designmRNA quantificationmagnetofluidic technologydroplet microfluidicsautomation in diagnosticsRNA sequencingspectroscopycell lysis techniques
Output against the department
Publications385top 19% of dept.52nd of 278
this lab
most publishedleast published
Citations12ktop 32% of dept.90th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.