University of Houston · EngineeringLupus Insight Lab
Chandra Mohan · Houston, Texas
Research Focus
Dr. Chandra Mohan's lab at the University of Houston focuses on advancing the diagnosis and treatment of systemic lupus erythematosus (SLE), particularly lupus nephritis (LN). Their research involves identifying and validating biomarkers that can help monitor disease progression and predict treatment response, aiming to improve patient outcomes. Additionally, they employ artificial intelligence and computer vision techniques to enhance histological diagnosis of kidney diseases associated with lupus, addressing the challenges of inter-pathologist variability.
lupuslupus nephritisbiomarkerscomputer visiondeep learningproteomicsrenal diseaseclinical validationmachine learningautoimmune diseases
Research Aims
5AIM 01Identify measurable biomarkers in body fluids to monitor lupus disease activity.
AIM 02Validate a set of ten proteins (LN-10-plex) across diverse patient cohorts.
AIM 03Develop a deep learning classifier to accurately diagnose lupus nephritis from histological images.
AIM 04Predict clinical outcomes based on baseline renal pathology assessments.
AIM 05Track disease progression in lupus patients non-invasively.
Skills the Lab Values
proteomicscomputer visiondeep learningbiomarker identificationclinical trialsdata analysisimage classificationPythonstatistical analysisHistology
Output against the department
Publications526top 11% of dept.30th of 278
this lab
most publishedleast published
Citations17ktop 24% of dept.66th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.