University of Minnesota-Twin Cities · Biomedical EngineeringCancer Immunotherapy Engineering Lab
David J. Odde · Minneapolis, Minnesota
Research Focus
Dr. David J. Odde's laboratory focuses on engineering innovative solutions for improving cancer immunotherapy, particularly for challenging cancers like pancreatic ductal adenocarcinoma and glioblastoma. By developing a multiscale tumor simulator, this team predicts tumor dynamics and the interaction between cancer cells and immune cells, guiding the development of more effective immunotherapies. The lab combines expertise in biomedical engineering, immunology, and genetic engineering to create a robust platform for cancer research and treatment.
immunotherapytumor simulationcancer engineeringbiomedical engineeringimmune responsegenome engineeringglioblastomapancreatic cancercomputational modeling
Research Aims
4AIM 01Develop a tumor simulator to predict immune and cancer cell dynamics.
AIM 02Integrate genome engineering into simulations to enhance immunotherapy applications.
AIM 03Test predictions made by the simulator through experimental validation.
AIM 04Collaborate across disciplines to refine immunotherapy strategies.
Skills the Lab Values
live cell microscopymultiscale modelingcomputational simulationgenetic engineering techniquespharmacological testingdata analysismicroenvironment engineeringcell cultureimmunological assays
Output against the department
Publications239top 43% of dept.254th of 595
this lab
most publishedleast published
Citations11ktop 33% of dept.196th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.