University of California-San Diego · ChemistryFluorescent Probes for Neurodegeneration Unit
Jerry Yang · La Jolla, California
Research Focus
Dr. Jerry Yang's lab focuses on creating advanced fluorescent probes that help in detecting amyloid formations in the brain, which are linked to neurodegenerative diseases like Alzheimer's, Parkinson's, and Frontotemporal Dementia. The research aims to improve diagnostic tools that can identify various forms of amyloid in living patients, enhancing early detection and treatment options. By developing methods to study amyloid deposits, the lab contributes significantly to understanding and managing these debilitating conditions.
amyloid detectionfluorescent probesAlzheimer's diseaseneurodegenerative diseasesearly diagnosis
Research Aims
3AIM 01Develop fluorescent probes that selectively detect amyloid aggregates in solutions and tissues.
AIM 02Create a method to analyze the distribution of amyloidogenic proteins in biofluids.
AIM 03Investigate the use of fluorescent probes for imaging amyloid deposits in the retina.
Skills the Lab Values
fluorescent probe designfluorescence microscopytissue imagingbiofluid analysisprotein characterization
Output against the department
Publications162bottom 39% of dept.131st of 216
this lab
most publishedleast published
Citations5.6kbottom 39% of dept.132nd of 216
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.