University of Texas Southwestern Medical Center · BiologyInfluenza Virus Export Lab
Beatriz Ma Fontoura · Dallas, Texas
Research Focus
Dr. Beatriz Ma Fontoura's lab focuses on understanding the nuclear export of influenza virus mRNA and how various proteins facilitate this process. By investigating specific RNA-binding proteins and their roles in the export pathways, the lab aims to uncover fundamental mechanisms of viral replication. This knowledge could lead to new antiviral strategies against influenza virus infections.
influenza virusmRNA exportRNA-binding proteinsTREX-2viral replicationcell biologybiochemistryviral gene expressionnuclear pore complexantiviral strategies
Research Aims
5AIM 01Define the role of RNA-binding proteins in influenza virus mRNA nuclear export.
AIM 02Characterize interactions between hnRNP proteins and viral mRNAs.
AIM 03Identify RNA-binding proteins that mediate differential nuclear export of viral mRNAs.
AIM 04Investigate the mechanisms of the TREX-2 mRNA export pathway.
AIM 05Explore structural interactions of proteins involved in mRNA export.
Skills the Lab Values
cell cultureRNA isolationbiochemical assaysimaging techniquesmolecular cloninggenetic screeningsingle molecule RNA FISHin vitro assaysmouse models
Output against the department
Publications84bottom 26% of dept.760th of 1,033
this lab
most publishedleast published
Citations6.0kbottom 44% of dept.582nd of 1,033
this lab
most citedleast cited
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