Duke University · NeurosciencePsoriatic Arthritis Pain Research Lab
Yong Chen · Durham, North Carolina
Research Focus
Dr. Yong Chen's lab at Duke University focuses on understanding and alleviating the pain associated with psoriatic arthritis (PsA), a painful joint condition that affects many individuals. They are developing improved animal models to explore the mechanisms of psoriatic arthritis pain, particularly examining the role of certain lipids in inflammation and pain pathways. The aim is to identify new therapeutic targets that could lead to better pain management for PsA patients.
psoriatic arthritispain mechanismsanimal modelsinflammationtherapeutic targets
Research Aims
3AIM 01Develop an improved animal model for studying psoriatic arthritis pain.
AIM 02Characterize the role of lysophosphatidylcholine in psoriatic arthritis pain.
AIM 03Identify new therapeutic targets for pain relief in psoriatic arthritis.
Skills the Lab Values
animal handlingpain measurement techniquesmouse modelsmolecular analysislipid profilinginjection techniquesdata collection and analysischronic pain studiesbiological assays