Yale University · Microbiology & ImmunologyIgE Function and Immune Response Unit
Ruslan Medzhitov · New Haven, Connecticut
Research Focus
Dr. Ruslan Medzhitov's lab at Yale University studies Immunoglobulin E (IgE), a type of antibody that plays a crucial role in the immune response. While IgE is well-known for causing allergies, the lab is interested in understanding its functions in maintaining health and fighting diseases. They aim to identify specific antigens that IgE responds to and how these interactions influence the body's response during infections and inflammation.
IgEhomeostasisimmune responseallergic diseaseantigens
Research Aims
3AIM 01Identify IgE reactivities in homeostasis
AIM 02Explore IgE's role in host protection against disease
AIM 03Contextualize IgE's effects during acute inflammatory responses
Skills the Lab Values
antibody purificationhigh-throughput screeningflow cytometrymicroscopygenetic engineeringmouse modelsimmunoassaysdata analysis
Output against the department
Publications346top 12% of dept.57th of 486
this lab
most publishedleast published
Citations130ktop 1% of dept.3rd of 486
this lab
most citedleast cited
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