Baylor College of Medicine · NeuroscienceReimer Lab
Jacob Reimer · Houston, Texas
Research Focus
Dr. Jacob Reimer's lab at Baylor College of Medicine investigates how the brain's neuromodulators, specifically acetylcholine and norepinephrine, influence sensory processing and attention. By experimenting with mice, the lab explores how these chemicals affect brain activity over space and time, which could enhance our understanding of cognitive functions and diseases such as Alzheimer’s and ADHD. The research seeks to clarify how neuromodulators contribute to the variability in responses to stimuli, potentially revealing new insights into attention mechanisms and treatment strategies.
neuromodulationacetylcholinenorepinephrinesensory processingattentionAlzheimer's diseaseADHDmouse modelsbehavioral taskscortical brain state
Research Aims
5AIM 01Investigate the spatial and temporal dynamics of acetylcholine and norepinephrine in the mouse brain.
AIM 02Assess the variability of neuromodulator availability across different cortical regions.
AIM 03Explore the independent recruitment of neuromodulators during auditory and visual tasks.
AIM 04Understand the impact of neuromodulatory systems on attention and performance.
AIM 05Establish a baseline for neuromodulator activity to identify potential changes in disease states.
Skills the Lab Values
neurophysiology techniquescalcium imaginganimal behavior experimentsfluorescent probe techniquesdata analysis in neuroscienceexperiment designelectrophysiologymultimodal stimulus testingbehavioral assessment in miceimmunohistochemistry
Output against the department
Publications112bottom 39% of dept.406th of 671
this lab
most publishedleast published
Citations8.1ktop 46% of dept.312th of 671
this lab
most citedleast cited
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