University of Chicago · BiochemistrySosnick Protein Lab
Tobin R Sosnick · Chicago, Illinois
Research Focus
Dr. Tobin R Sosnick's lab at the University of Chicago focuses on understanding how proteins, especially membrane and disordered proteins, work and fold. They use advanced techniques to study how these proteins transport molecules across cell membranes and how they behave under stress. This research is not only foundational for biology but also has practical implications for drug development and understanding disease processes.
membrane proteinsdisordered proteinsprotein foldingbiophysical chemistrymetabolite transport
Research Aims
5AIM 01Investigate the dynamics and folding of membrane proteins
AIM 02Study the transport of metabolites across cellular membranes
AIM 03Examine the properties of disordered proteins
AIM 04Explore stress-induced phase separation in proteins
AIM 05Enhance methods for studying protein biophysics.
Skills the Lab Values
hydrogen exchangecell membrane studiesprotein characterizationmass spectrometrycomputational modeling
Output against the department
Publications290top 23% of dept.92nd of 402
this lab
most publishedleast published
Citations15ktop 33% of dept.132nd of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.