Stanford University · GeneticsThe Enzyme Mapping Lab
Alice Y Ting · Stanford, California
Research Focus
Dr. Alice Y Ting's lab focuses on developing innovative enzymes that improve the mapping of proteins within living cells. Their research aims to create more effective methods for studying how proteins interact and organize within cells, which is essential for understanding various biological processes and diseases. By enhancing existing techniques and creating new ones, the lab seeks to advance our tools for exploring cellular dynamics and potential treatments for diseases.
proximity labelingspatial proteomicsmolecular interactionscell biologyneuroscienceimmunologyenzyme engineering
Research Aims
4AIM 01Develop next-generation proximity labeling enzymes to improve spatial proteome mapping.
AIM 02Optimize FlexID for rapid and specific labeling of protein interactions.
AIM 03Engineer LaccID for enhanced surface protein labeling and reduced background interference.
AIM 04Benchmark and compare various proximity labeling methodologies for sensitivity and specificity.
Skills the Lab Values
protein engineeringmass spectrometrycomputational designdirected evolutionlabeling techniquescell culturebiochemical fractionationquantitative proteomicsdata analysis
Output against the department
Publications224top 38% of dept.98th of 259
this lab
most publishedleast published
Citations31ktop 19% of dept.49th of 259
this lab
most citedleast cited
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