North Carolina State University at Raleigh · BiologySaini Asthma Lab
Yogesh Saini · Raleigh, North Carolina
Research Focus
Dr. Yogesh Saini's lab at North Carolina State University focuses on understanding how air pollution, particularly ozone, affects allergic asthma. They study the biological processes involved in the inflammation and healing of respiratory conditions. By investigating specific signaling pathways, the lab aims to find new ways to treat and manage respiratory diseases linked to air pollution and allergies.
allergic asthmaozone exposureinflammationIL-33 signalingrespiratory diseaseair pollutionTh2 responsesresolution of inflammationpharmacological inhibitorsbone marrow chimeras
Research Aims
3AIM 01Investigate the role of IL-33 in Th2 inflammation among different cell types.
AIM 02Examine how ozone exposure affects the healing process of allergic inflammation in the lungs.
AIM 03Test the effects of inhibiting IL-33-ST2 signaling on ozone-disrupted inflammation resolution.
Skills the Lab Values
cell culturemouse modelsPCRflow cytometryWestern blotRNA sequencinggenetic manipulationin vivo imagingimmunohistochemistrysignal transduction assays
Output against the department
Publications99bottom 35% of dept.674th of 1,033
this lab
most publishedleast published
Citations1.1kbottom 5% of dept.977th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.