WMCWeill Medical College of Cornell University · Neuroscience
Pearson Metabolism Lab
Caroline Alayne Pearson · New York, New York
Research Focus
Dr. Caroline Alayne Pearson's lab at Weill Medical College of Cornell University investigates how glucose transport impacts brain development and disorders. The lab focuses on understanding the role of a specific glucose transporter in neural progenitor cells and its relevance to conditions like GLUT1-Deficiency Syndrome. Through cutting-edge techniques, researchers study how changes in glucose regulation affect neural cell development and function.
Glucose Transporter 1Neural DevelopmentNeurodevelopmental DisordersGLUT1-Deficiency SyndromeCell Fate DecisionsNeural Progenitor CellsCerebral OrganoidsMetabolismCorticogenesis
Research Aims
4AIM 01Determine how glucose uptake is regulated in neural progenitor cells during neurogenesis.
AIM 02Investigate the impact of GLUT1 expression on cell proliferation and differentiation in mouse models.
AIM 03Examine human cerebral organoids with GLUT1 mutations to assess neuronal function and cortical differentiation.
AIM 04Explore metabolic changes associated with GLUT1 loss and their effects on brain development.
Skills the Lab Values
ImmunohistochemistryFluorescent In Situ HybridizationSingle Cell TranscriptomicsCerebral Organoid CulturingMetabolomic AssaysProteomic AnalysisMouse ModelsCell CultureData Analysis
Output against the department
Publications29bottom 5% of dept.637th of 671
this lab
most publishedleast published
Citations1.3kbottom 7% of dept.625th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.