University of Minnesota-Twin Cities · PharmacologyThe NeuroAging Lab
Ling Li · Minneapolis, Minnesota
Research Focus
Dr. Ling Li's lab at the University of Minnesota focuses on understanding the biochemical changes that lead to Alzheimer's disease and the effects of COVID-19 on the brain. The lab investigates how variations of the apolipoprotein E (APOE) gene and mitochondrial lipids interact to influence brain aging and cognitive function. They utilize advanced techniques to study brain pathology in aging and how infections like SARS-CoV-2 may exacerbate cognitive impairments.
Alzheimer's DiseaseAPOEmitochondrial dynamicsbrain agingSARS-CoV-2lipidomicscognitive functionneuropathologyneuroinflammation
Research Aims
3AIM 01Investigate how APOE isoforms affect mitochondrial lipid dynamics during brain aging.
AIM 02Examine the link between mitochondrial lipid profiles and cognitive decline in Alzheimer's models.
AIM 03Explore how SARS-CoV-2 infection alters neuroinflammation and cognitive function in aging populations.
Skills the Lab Values
lipidomicsmouse models3D imagingtranscriptomicsanimal behavior assessmentcell cultureimmunohistochemistryvirologybioinformatics
Output against the department
Publications924top 3% of dept.12th of 462
this lab
most publishedleast published
Citations31ktop 8% of dept.38th of 462
this lab
most citedleast cited
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