Columbia University in the City of New York · Microbiology & ImmunologyThe ImmunoBoost Lab
Steven L Reiner · New York, New York
Research Focus
Dr. Steven L. Reiner's lab at Columbia University focuses on understanding how to improve cancer immunotherapy, which harnesses the body's immune system to fight cancers. The lab is investigating mechanisms of T cell behavior in response to cancers and how to enhance their ability to persist and effectively attack tumors. Ultimately, their work aims to develop better predictive tests for treatment response and advanced strategies for patients who do not respond well to current therapies.
cancer immunotherapyT cell biologyimmune checkpoint blockadebiomarkersCD8+ T cells
Research Aims
3AIM 01Investigate the self-renewal capabilities of CD8+ T cells in relation to cancer immunotherapy.
AIM 02Develop a predictive biomarker for patient response to immunotherapy.
AIM 03Enhance CD8+ T cell self-renewal to improve immunotherapy outcomes.
Skills the Lab Values
cell cultureflow cytometryimmunotherapy techniquesconfocal microscopyRNA sequencing
Output against the department
Publications191top 34% of dept.164th of 486
this lab
most publishedleast published
Citations25ktop 14% of dept.67th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.