Augusta University · BiologyTang Cardiac Lab
Yao Liang Tang · Augusta, Georgia
Research Focus
Dr. Yao Liang Tang's lab studies how specific enzymes affect heart cells after injury. They focus on transforming problematic heart cells into those that can help repair heart damage. This research is important because it could lead to new treatments for heart failure, a condition where the heart struggles to pump blood effectively.
cardiac repairfibrosismyofibroblastsepigeneticscardiovascular health
Research Aims
5AIM 01Investigate the role of EZH2 in cardiac myofibroblasts.
AIM 02Transform myofibroblasts from a pro-fibrotic to a pro-angiogenic phenotype.
AIM 03Assess the impact of EZH2 inhibition on heart repair after myocardial infarction.
AIM 04Evaluate the therapeutic potential of EZH2 inhibitors for treating heart failure.
AIM 05Explore mechanisms of cardiac regeneration at the molecular level.
Skills the Lab Values
single-cell RNA sequencing (scRNA-seq)gene deletion techniquescardiac cell culturein vivo mouse modelschromatin remodeling assays
Output against the department
Publications262top 23% of dept.235th of 1,033
this lab
most publishedleast published
Citations8.6ktop 44% of dept.458th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.