RUThe Rockefeller University · Microbiology & Immunology
Viral Immunology and Therapeutics Lab
Marina Caskey · New York, New York
Research Focus
Dr. Marina Caskey's lab at Rockefeller University focuses on understanding and combating viral infections, particularly HIV and hepatitis B virus (HBV). The lab conducts innovative research to investigate how HIV escapes treatments with broadly neutralizing antibodies (bNAbs) and explores new therapeutic strategies for chronic HBV infection. The goal is to improve immune responses and develop effective treatments that can lead to long-term remission of these viral infections.
HIVbroadly neutralizing antibodieshepatitis B virusviral resistanceimmune response
Research Aims
4AIM 01Identify mechanisms of HIV resistance to broadly neutralizing antibodies in humans.
AIM 02Map bNAb resistance mutations across diverse viral strains.
AIM 03Characterize bNAb-resistant HIV-1 variants in cell culture.
AIM 04Evaluate the safety and efficacy of mAb19 in human trials for HepB.
Skills the Lab Values
cell culturenext generation sequencinganimal modelsflow cytometrycomputational modeling
Output against the department
Publications165top 40% of dept.193rd of 486
this lab
most publishedleast published
Citations24ktop 15% of dept.72nd of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.