Syracuse University · EngineeringZheng Lab
Yi Zheng · Syracuse, New York
Research Focus
Dr. Yi Zheng's lab at Syracuse University focuses on understanding human primordial germ cells, which are the precursors to eggs and sperm. Researchers in this lab are developing innovative stem cell models to study the intricacies of human embryonic development, especially how these germ cells form and migrate. This research aims to uncover fundamental mechanisms that could lead to breakthroughs in infertility treatment and regenerative medicine.
primordial germ cellshuman reproductionstem cell modelsembryonic developmentWnt signalinginfertilitygenetic diseasesmicrofluidics
Research Aims
4AIM 01Develop stem cell-based models to study human primordial germ cell development.
AIM 02Investigate the maturation and migration of primordial germ cells using co-development models.
AIM 03Elucidate the roles of Wnt signaling in germ cell lineage commitment and migration.
AIM 04Utilize innovative lineage tracing to understand the origin of primordial germ cells.
Skills the Lab Values
stem cell culturemicrofluidicssingle-cell RNA sequencinglineage tracinggenome editingbioinformaticsembryoid model developmentmigration assayscell signaling analysis
Output against the department
Publications534top 10% of dept.27th of 278
this lab
most publishedleast published
Citations30ktop 10% of dept.27th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.