AECAlbert Einstein College of Medicine · Biology
Bouhassira Hematology Lab
Eric E. Bouhassira · Bronx, New York
Research Focus
Dr. Eric E. Bouhassira's lab at Albert Einstein College of Medicine focuses on developing new methods to produce cultured red blood cells (cRBCs) from stem cells. This innovative research aims to improve transfusion therapies, especially for patients with sickle cell disease by creating reliable sources of red blood cells with known antigen profiles. The work promises significant advancements in addressing the challenges of alloimmunization and providing effective transfusion support.
cultured red blood cellssickle cell diseaseinduced pluripotent stem cellstransfusion medicinealloimmunizationhemoglobin productionbioreactor technologycell characterizationstem cell researchrare blood donors
Research Aims
4AIM 01Develop a method for the large-scale production of cultured red blood cells.
AIM 02Characterize cultured red blood cells to assess their morphology and functionality.
AIM 03Produce reagent red blood cells from a panel of rare blood donors for antibody identification.
AIM 04Generate adult red blood cells that can proliferate without cytokines.
Skills the Lab Values
cell cultureinduced pluripotent stem cell generationgenetic mutation techniquesbioreactor operationcell characterization methodsflow cytometryanimal models experimentationmolecular cloningstem cell proliferation techniquesantibody testing
Output against the department
Publications229top 27% of dept.277th of 1,033
this lab
most publishedleast published
Citations8.5ktop 45% of dept.465th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.