Virginia Commonwealth University · GeneticsSarkar Lab
Devanand Sarkar · Richmond, Virginia
Research Focus
Dr. Devanand Sarkar's lab at Virginia Commonwealth University focuses on understanding liver cancer, specifically hepatocellular carcinoma (HCC) that arises from obesity-related conditions like non-alcoholic steatohepatitis (NASH). The lab aims to develop new treatment strategies by exploring the molecular mechanisms involved in HCC and testing these strategies using mouse models. Their work seeks to improve the current therapeutic options and ultimately enhance patient outcomes.
Hepatocellular carcinomaNASHobesityimmunotherapymolecular mechanismstyrosine kinase inhibitorscombination therapymouse modelsbioinformaticsliver cancer
Research Aims
5AIM 01Investigate molecular mechanisms of HCC related to obesity and NASH.
AIM 02Develop new combinatorial treatment approaches for HCC.
AIM 03Evaluate the effectiveness of existing immunotherapy in NASH-HCC.
AIM 04Utilize mouse models to test novel therapeutic strategies.
AIM 05Create translational data to improve clinical treatment options for HCC patients.
Skills the Lab Values
PCRmouse modelsbiostatisticsbioinformaticscell cultureWestern blotin vivo imagingdrug delivery systemsimmunohistochemistryRNA sequencing
Output against the department
Publications684top 8% of dept.20th of 259
this lab
most publishedleast published
Citations22ktop 25% of dept.65th of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.