University of Pittsburgh-Pittsburgh Campus · Microbiology & ImmunologyHinterleitner Lab
Reinhard Hinterleitner · Pittsburgh, Pennsylvania
Research Focus
Dr. Reinhard Hinterleitner's lab studies celiac disease, focusing on how certain gut protists can help the immune system tolerate gluten. This innovative research looks at the relationship between these protists and immune cells to develop potential treatments for individuals at risk of developing celiac disease. By understanding these interactions, the lab aims to create new therapies that could help prevent food-related immune issues.
celiac diseasegluten intolerancegut protistsimmune tolerancedendritic cells
Research Aims
5AIM 01Investigate how gut protists influence immune responses to gluten.
AIM 02Determine the role of Parabasalia in promoting oral tolerance in celiac disease models.
AIM 03Examine the effect of enteric viruses on gluten-related immune responses.
AIM 04Develop novel therapies based on gut protists to prevent celiac disease.
AIM 05Explore the mechanisms by which dendritic cells interact with dietary antigens.
Skills the Lab Values
cell culturenext-generation sequencingmouse modelsimmunological assaysdata analysis
Output against the department
Publications45bottom 8% of dept.446th of 486
this lab
most publishedleast published
Citations3.2kbottom 23% of dept.376th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.