The University of Texas Health Science Center at San Antonio · Microbiology & ImmunologySalamango Virology Lab
Daniel James Salamango · San Antonio, Texas
Research Focus
Dr. Daniel James Salamango's lab explores the mechanisms behind HIV persistence, particularly focusing on how the HIV protein Vpr affects myeloid cells, like macrophages. They aim to understand how Vpr-induced changes in the cell's genetic material can help the virus survive in these cells, which could lead to new treatments for HIV. The findings could also contribute to the broader goal of finding a cure for HIV infection.
HIV persistenceepigenetic remodelingmyeloid cellsVpr proteinviral reservoirs
Research Aims
3AIM 01Investigate how Vpr modifies the nuclear environment to support HIV persistence.
AIM 02Characterize the effects of Vpr on HIV gene activation in infected cells.
AIM 03Identify the interaction partners of Vpr that influence its function.
Skills the Lab Values
PCRcell cultureflow cytometryWestern blotchromatin analysis
Output against the department
Publications73bottom 23% of dept.374th of 486
this lab
most publishedleast published
Citations1.4kbottom 8% of dept.446th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.