Rutgers University-New Brunswick · PharmacologyGlucose Sensing and Neuroscience Lab
Vanessa H Routh · New Brunswick, New Jersey
Research Focus
Dr. Vanessa H. Routh's lab studies the effects of low blood sugar in people with diabetes, particularly how the brain senses these dangerous drops. They use innovative animal models to examine the roles of certain neurons in this process and the potential of the drug modafinil to restore awareness of hypoglycemia. This research is crucial for developing better treatments for diabetic patients who suffer from dangerous hypoglycemia without realizing it.
diabeteshypoglycemianeuroscienceanimal modelsmodafinilglucose sensingorexin neuronsbrain responseblood sugar regulationdiabetic complications
Research Aims
5AIM 01Investigate how recurrent hypoglycemia affects brain neuron function.
AIM 02Determine the role of modafinil in restoring hypoglycemia awareness.
AIM 03Explore the mechanisms behind glucose sensitivity in orexin neurons.
AIM 04Assess the impact of dopaminergic pathways in hypoglycemia awareness.
AIM 05Elucidate how hyperglycemia influences hypoglycemia awareness.
Skills the Lab Values
mouse modelspatch clamp electrophysiologybehavioral assaysblood glucose measurementimmunohistochemistrypharmacologydata analysissurgery for animal studiesneuroanatomy techniquesexperimental design
Output against the department
Publications85bottom 19% of dept.371st of 462
this lab
most publishedleast published
Citations5.8kbottom 42% of dept.268th of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.