Indiana University-Bloomington · ChemistrySingle-Particle Microfluidics Lab
Stephen C Jacobson · Bloomington, Indiana
Research Focus
Dr. Stephen C. Jacobson's lab focuses on developing advanced tools to study viruses, bacteria, and extracellular vesicles at a single-particle level. They use micro- and nanofluidic devices to gain insights into these biological entities, particularly how they behave over time and under different conditions. The research is significant for understanding complex biological processes and could lead to better medical treatments.
microfluidicsvirus capsidsextracellular vesiclesbacteriasingle-particle analysisglycan profilingcapillary electrophoresisspatiotemporal resolutionhigh-throughput multiplexing
Research Aims
5AIM 01Develop micro- and nanofluidic devices for single-particle analysis of biological systems.
AIM 02Investigate virus capsid assembly and disassembly using resistive-pulse sensing.
AIM 03Monitor bacterial growth and behavior using integrated nanochannel arrays.
AIM 04Profile glycans from biological fluids and extracellular vesicles for detailed characterization.
AIM 05Analyze the relationship between glycan properties and the behavior of extracellular vesicles.
Skills the Lab Values
microfluidic device fabricationsingle-particle trackingfluorescence microscopycapillary electrophoresisresistive-pulse sensingdata analysiscell cultureglycan analysisimaging techniques
Output against the department
Publications231top 47% of dept.102nd of 216
this lab
most publishedleast published
Citations14ktop 35% of dept.76th of 216
this lab
most citedleast cited
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