University at Buffalo · Biomedical EngineeringLovell Lab
Jonathan F Lovell · Buffalo, New York
Research Focus
The lab led by Dr. Jonathan F. Lovell focuses on innovative approaches to tackle some of the most challenging health issues, such as tuberculosis and pancreatic cancer. Through the development of advanced vaccine technologies and light-activated drug delivery systems, the lab aims to improve treatment efficacy significantly and contribute to better patient outcomes. Students involved in this lab will gain hands-on experience with cutting-edge biomedical engineering techniques and contribute to groundbreaking research in vaccine development and cancer therapies.
tuberculosis vaccinepancreatic cancernanotechnologydrug deliveryliposomeschemophototherapyimmunotherapyvaccine developmenttumor ablation
Research Aims
5AIM 01Develop a multivalent vaccine for tuberculosis using engineered nanoliposomes.
AIM 02Evaluate the immunogenicity of tuberculosis antigens displayed on particle surfaces.
AIM 03Translate light-activated drug delivery methods to enhance treatment for pancreatic cancer.
AIM 04Optimize interstitial chemotherapy protocols for application in large tumors.
AIM 05Investigate the combination of immune checkpoint blockade with nanotechnology for improved cancer treatment.
Skills the Lab Values
PCRcell culturemouse modelstumor xenograft modelsflow cytometryliposome formulationimmunization techniquespharmacokinetics analysisphototherapy techniques
Output against the department
Publications415top 22% of dept.127th of 595
this lab
most publishedleast published
Citations21ktop 15% of dept.89th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.